Association of In Utero Persistent Organic Pollutant Exposure With Placental Thyroid Hormones
نویسندگان
چکیده
منابع مشابه
Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome
BACKGROUND The incidence of the insulin resistance syndrome has increased at an alarming rate worldwide, creating a serious challenge to public health care in the 21st century. Recently, epidemiological studies have associated the prevalence of type 2 diabetes with elevated body burdens of persistent organic pollutants (POPs). However, experimental evidence demonstrating a causal link between P...
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Background and aims Particulate matter exposure during in utero life may entail adverse health outcomes later in life. Epidemiological studies in adults have linked air pollution’s adverse effects to alterations in gene expression profiles, which can be regulated by epigenetic mechanisms, including microRNAs (miRNAs). MiRNAs have been implicated in diverse biological processes. We investigate t...
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Perfluoroalkyl substances (PFASs) have been detected in wildlife and human samples worldwide. Toxicology research showed that PFASs could interfere with thyroid hormone homeostasis. In this study, eight PFASs, fifteen PFAS precursors and five thyroid hormones were analyzed in 157 paired maternal and cord serum samples collected in Beijing around delivery. Seven PFASs and two precursors were det...
متن کاملMaternal blood levels of persistent organic pollutants can be used to estimate in utero exposure.
The presence of persistent organic pollutants (POPs) in the fetal environment raises concerns for their possible interferences with the developmental process, resulting into morphological and/or functional impairments of the organism. Human biomonitoring has been widely recognized as the action to be undertaken to characterize children's exposure to environmental pollutants in the different lif...
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BACKGROUND Fish are a source of persistent organic pollutants (POPs) in the human diet. Although species, trophic level, and means of production are typically considered in predicting fish pollutant load, and thus recommendations of consumption, capture location is usually not accounted for. OBJECTIVES Yellowfin tuna (Thunnus albacares) are harvested from across the world's oceans and are wid...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2018
ISSN: 1945-7170
DOI: 10.1210/en.2018-00542